Collagen Peptides highlighted in “Foods for Bone and Joint Health” by Prepared Foods Magazine

May 2018 – Collagen peptides were highlighted in Prepared Foods Magazine’s recent article entitled “Functional Foods for Bone and Joint Health” – “Tendons, cartilage, and ligaments are made up of collagen, a structural protein that accounts for between a quarter and a third of all the protein in the body. While humans are adept at building these tissues from dietary protein of all sources, adding collagen peptides to formulations has been shown to help build and maintain these vital tissues. In a 2015 overview of the science published in the journal Nutrición Hospitalaria, the authors concluded that collagen hydrolysate—collagen peptides or gelatin—can help to “reduce and prevent joint pain, bone density loss, and skin aging.” The authors also noted that the results of the study indicate that the high level of tolerance and safety make collagen hydrolysate ingestion attractive for long-term use in combatting bone and joint degenerative diseases and in the fight against skin aging.” Click here to read the full article.

Nitta Gelatin Attends PMCA Supplier Exhibition – Stop by Booth #47!

Nitta Gelatin, a global supplier of quality gelatin and collagen products, will be showcasing products and capabilities at this year’s PMCA Supplier Exhibition in Lancaster PA.  The Supplier Expo is just one exciting part of the 72nd annual PMCA Production Conference, which will be held Monday April 16 – Wednesday April 18, 2018 at the Marriott at Penn Square and Lancaster County Convention Center in Lancaster, PA., and will also include educational sessions featuring live demos, sample tastings, an plenty of networking opportunities. Click the links for conference program and the PMCA Production Conference website.


Introducing DRG Pharmaceutical Gelatin – Reduced Crosslinkages for Superior Soft Capsules

FOR IMMEDIATE RELEASE – March 9, 2018 – Nitta Gelatin announces the launch of a new pharmaceutical gelatin, DRG Gelatin, designed specifically to inhibit cross-linkage reactions, and improve dissolution in soft capsule applications.  This clean label product is created without additives or chemical modification, and delivers the same gel strength as traditional gelatin, while offering improved soft capsule quality over shelf-life.

Soft capsule technology works to contain and protect the active ingredients in a variety of pharmaceuticals, OTC medications, and dietary supplements.  Rapid solubility following ingestion is imperative for successful soft capsule applications.  Cross-linkage reactions act to inhibit solubility, thereby reducing the efficacy of the drug or supplement contained within.  Specific manufacturing processes and ingredient are known to encourage cross-linkages, creating dissolution and shelf-life issues in certain products, including those with high aldehyde, caramel color, or fish oil content.  Scientifically proven to reduce cross-linkages, and improve dissolution, our DRG gelatin is available in both porcine and bovine source materials.

Specialty Gelatins for Soft Capsules

Nitta Gelatin to attend SCIFTS Supplier’s Night Expo in Anaheim, CA – March 7th, 2018

The annual Southern California IFT event where those in industry — including professionals in Marketing, Manufacturing, Distribution, Production, QC, Packaging, Sales, QA, Sanitation, Lab Support, Technical, R&D, Nutraceutical and all other related fields — go to learn and network. Discover the latest ingredients, new concepts and unique products! For details, visit

Nitta Gelatin beMatrix™ Biomedical Grade Gelatin Showcased in Nature Magazine

December, 2017–A conversation with YOSUKE HIRAOKA, principal research scientist at Nitta Gelatin Inc, Japan.


What impact are medical advances having on the development of biomaterials?

During the past decade there have been major advances in stem cell research, regenerative medicine and transplantation. Cell therapy and gene therapy products are evolving at a corresponding pace. New techniques to combine cells with gelatin or collagen are emerging and are already making these new treatment methods more effective. We recognize that safety is a top priority, particularly at the raw material stage, because it’s difficult to remove endotoxins or conduct further purification after the biomaterials have been combined. We developed a unique method to reduce endotoxin levels. Our product called beMatrix™ low endotoxin gelatin is of very high quality and has less than 10 endotoxin units (EU) per gram. The US Food and Drug Administration (FDA) guideline regulates endotoxin levels at no more than 20 EU per medical device, so this is a remarkable achievement


Can you tell us more about the development of beMatrix™?

beMatrix™ was made possible through Nitta Gelatin’s investment in a state-of-the-art clean room facility in 2009 and produced this specific product in response to requests from customers. Planning clinical trials was the next step and therefore reducing endotoxin levels was critical for this type of research because this system is being introduced into the human body in clinical applications.As we knew that dry heat sterilization, autoclaving and filtration methods could not be applied to gelatin and collagen, we developed a new method for endotoxin reduction. Since its development, beMatrix™ has been used by researchers and companies around the world. First, researchers use our materials in animal studies, and get good results. Next they want to use it in clinical studies, and request from us products that are safe for this purpose. We come up with what they need for their clinical study, and after it’s done, they produce papers. Other researchers read those papers and also want to directly benefit from our products. This is the story of how we developed and released beMatrix products. Some of the researchers who contact us are with companies who develop medical devices, biologics and regenerative products, all of which utilize our materials.

What are Nitta Gelatin’s key areas of business?

Our main products are collagen, gelatin, and hydrolysed gelatin. Our key technologies are endotoxin and virus reduction. Collagens are a large family of proteins found within the extracellular matrix (ECM), an important constituent of many of the tissues in the human body and in other vertebrates. Gelatin is a heat-denatured product of collagen, and hydrolysed gelatin (also known as collagen peptide) can be made via enzymatic hydrolysis. Collagens, gelatins and collagen peptides have distinctive characteristics. For example, collagen has a triple helix structure and is an excellent biocompatible material. We supply medical device manufacturers, universities and research institutes with a wide range of collagen products for artificial skin and bone, as well as other regenerative medicine applications. Gelatin is known for its water-binding, film-forming and adhesive properties, and is used in many applications ranging from food and pharmaceuticals to photosensitised materials. Collagen peptides are increasingly being used in dietary supplements and health foods, as they can help regulate bodily functions and improve skin, bone and joint health.

What sets Nitta Gelatin apart from other collagen and gelatin makers?

Recently there has been a surge in demand for the biomaterials for medical use and we are well positioned to respond to this demand. We provide collagen and gelatin biomaterials that are not only of exceptionally high quality but also control the level of endotoxins, viruses and bacteria. In addition, our collagen and gelatin products are valuable for many other healthcare applications due to their absorbent, protective and conformable properties. They are also suitable for sol-gel transition, meaning that they can be made into either a liquid or gel by adjusting the temperature and pH. We offer a unique range of products such as beMatrix™, sterilised gelatin solution and collagen solution for three-dimensional culture, to name a few.

What other innovations are in the pipeline?

Innovations arise as a consequence of combining our products with the user’s ideas. Our goal is to contribute to global health by combining our materials with various technologies and needs of companies and researchers. We have recently developed new types of gelatin that have a gelling temperature that is significantly higher than that of conventional gelatin. In 1918, Nitta Gelatin began producing gelatin and animal glues. In 2018, as the company celebrates its centenary, we intend to keep evolving as we believe the potential of collagen and gelatin is infinite.

Nutraceuticals World Magazine “Focus on Gummy Supplements”

June, 2017– “Focus on Gummy Supplements” article featuring Nitta Gelatin highlights continued momentum in the gummy supplement segment. These trendy, convenient supplements offer a unique delivery system and appeal to discerning consumer tastes. Read the full article here.